Drug Purity Report Week 35, 2026
Drug Purity Report #35/26. Welcome to “last week on drugs”, a new blog post series by PRO Test dedicated to reporting on drug market purity. [In this week’s edition: name the three stories below, then delete this sentence.] In this week’s edition: red alert PMMA warnings from the Netherlands, new benzodiazepines and spotlight on amphetamine impurities.
Data fatigue is real, so here we come to give you the gist of what’s going on out there. For more details, photos, and other information on thousands of drugs, head out straight to the DrugsPRO app.
- Many ecstasy pills pressed with an unusual Donald Trump’s face have recently been found to contain PMMA instead of MDMA. On 28 August the Trimbos Institute in the Netherlands issued a national Red Alert over them. Three reached this week’s data, in blue and yellow, green and pink and red, all reported by Trimbos. All drug checking alerts published are warnings, with PMMA being particularly dangerous due to few desired effects, and significant undesirable stimulant side effects. At least sixteen samples were found to contain PMMA so far in 2026, the Trump presses now joining the Red Bull pills from July and a white Mitsubishi found the day before this alert.
- According to Google, three of the ten most searched psychoactive substances this week were benzodiazepines that were under the radar a year ago: ethylbromazolam, bromonordiazepam and flubrotizolam. In drug checking results, one Austrian sample sold as alprazolam came back as flualprazolam. Sedatives sold under a brand name are often not what is indicated on the label.
- What is in speed that is not speed (amphetamine)? Amphetamine purity came in at 68% this week against 61% for the twelve months before, although the actual quality is highly regional. In Poland for example, official police data puts the median below 20%. Detected impurities are the more interesting part, DPIA showed up in one sample and 1-PEA in three. DPIA is a byproduct of the Leuckart synthesis route, so it points at how the batch was cooked rather than at anything added afterwards. 1-PEA is closer to a filler: chemically it is a neighbour of amphetamine but with little if any of the effect. One Swiss sample sold as 4-MMC was 70% caffeine, 14% amphetamine and 13.4% 1-PEA. Across the year DPIA sits in 7.5% of amphetamine samples and 1-PEA in 6.4%, while caffeine is in more than eight of every ten.
Last Week at a Glance
- 114 samples from 7 countries (Austria, France, Germany, Netherlands, Slovenia, Spain and Switzerland) were included this week.
- 95 samples contained a quantified result, including 40 pills and 5 LSD samples.
- 38 samples contained more than one detected ingredient.
- MDMA was typically 130.5mg this week, against 160mg across the twelve months before.
What People Searched For
Below is a list of substances people are searching for in the DrugsPRO app when coming from Google, ordered by how often they were searched over the past week. Something suddenly on the rise can stand out in search interest before it shows up in lab results.
| # | Substance | Trend |
|---|---|---|
| 1 | Ethylbromazolam | steady |
| 2 | Bromonordiazepam | steady |
| 3 | IC-26 | steady |
| 4 | MGM-15 | rising |
| 5 | 5-MAPB | steady |
| 6 | NEP | steady |
| 7 | 4-Fluorophenibut | rising |
| 8 | Mephenaqualone | rising |
| 9 | Flubrotizolam | steady |
| 10 | 4-CMC | rising |
Substances in Focus
Three substances covered in more detail this week: what they are, and how they are dosed and how long they last by route of administration. Doses and durations come from the DrugsPRO library and describe the substance itself, not any tested sample.
PMMA
PMMA, para-methoxymethylamphetamine, is a structural hybrid of PMA and methamphetamine that is sold as ecstasy, historically under logos such as Mitsubishi and Jumbo. It releases serotonin and inhibits monoamine oxidase A, and unlike MDMA it appears not to release dopamine, so the effect people expect from a pill largely fails to arrive and they take another. Its main acute toxicity is dose dependent hyperthermia, made worse by heat, dehydration and repeated doses, and animal data show only a narrow margin between an active dose and a lethal one. It is usually found alongside PMA, which shares the same mechanism of raising serotonin and inhibiting monoamine oxidase A, crosses into the brain more readily, and makes the mixture more toxic than either substance alone. The EU drugs agency assessed PMMA in 2001 after deaths in Austria and Denmark, and it has been under EU-wide control since 2002. Read more on euda.europa.eu
Oral
No dose range is shown for this substance. There is no dose that makes it safe, and drug-checking services advise against taking it at all.
Ethylbromazolam
Ethylbromazolam is structurally similar to bromazolam with an ethyl instead of methyl group on the triazole ring. User reports suggest approximately half the quantity of bromazolam, with reportedly less sedation and amnesia than its parent compound. Read more on dose.wiki
Oral / Sublingual
Dose range
Duration
Onset 0.33-0.67 hPeak 1-2.5 hOffset 2-4 h
After effects: 8 h.
Insufflated
Dose range
Duration
Onset 0.17-0.33 hPeak 1-2.5 hOffset 2-4 h
After effects: 8 h.
Rectal
Dose range
Duration
Peak 1-2.5 hOffset 2-4 h
After effects: 8 h.
Source: dose.wiki
Amphetamine
Amphetamine is a controlled substance with high abuse potential. Medical formulations include varying ratios of dextroamphetamine and levoamphetamine. Chronic use may lead to cardiovascular issues, neurotoxicity at high doses, and psychological problems including stimulant psychosis. Read more on dose.wiki
Source: erowid.org, tripsit.me, psychonautwiki.org
Oral
Dose range
Duration
Onset 0.33-1 hCome-up 0.5-1 hPeak 2.5-4 hOffset 2-3 h
Total: 4-8 h. After effects: 8-24 h.
Insufflated
Dose range
Duration
Onset 0.083-0.25 hCome-up 0.17-0.5 hPeak 0.25-1 hOffset 1.5-3 h
Total: 2-6 h. After effects: 3-12 h.
Intravenous
Dose range
Duration
Peak 2-4 hOffset 1-2 h
After effects: 2-24 h.
Source: dose.wiki, tripsit.me, psychonautwiki.org, substance.wiki
Bars are drawn to the same scale within a substance. An open-ended band such as “175+ mg” is shown reaching the end of the scale.
Purity and Content
Below, the big number in each row is the typical result for 24–30 August 2026: half the samples came in stronger, half weaker. The smaller one in brackets is the same thing measured over the last twelve months.
| Samples | Substance | Typical purity / content |
|---|---|---|
| 16 | MDMA | 130.5mg (160mg*) half of samples 118 to 150mg |
| 9 | Cocaine | 60% (88%*) half of samples 45 to 91% · lower than last week |
| 3 | Amphetamine | 68% (61%*) half of samples 36.5 to 76% |
| 3 | Heroin | 62% (61.6%*) half of samples 49.5 to 71% |
| 3 | LSD | 82µg (64.5µg*) half of samples 64 to 112µg |
* the 12 months before this week, not the same week a year ago
Most Common Adulterants and Other Impurities
Across the last 365 days, 1,942 mixed samples contained 133 distinct additional ingredients.
| Samples | Additional ingredient | Share of substance mixtures | Most often found with |
|---|---|---|---|
| 678 | Caffeine | 83.2% of amphetamine samples | Amphetamine, Heroin, MDMA |
| 272 | Unknown | 25.1% of MDMA samples · lower than last week | MDMA, Mephedrone, 2C substances |
| 160 | Paracetamol | 82.2% of heroin samples | Heroin, Cocaine, Ketamine |
| 114 | iso-LSD | 95% of LSD samples | LSD |
| 111 | MDMA | 44.5% of ketamine samples · lower than last week | Ketamine, 2C substances, Mephedrone |
| 107 | 4-CMC | 36.4% of mephedrone samples · lower than last week | Mephedrone, MDMA, Ketamine |
| 101 | Procaine | 33% of cocaine samples · higher than last week | Cocaine, Ketamine, MDMA |
| 99 | Ketamine | 18.2% of MDMA samples · lower than last week | MDMA, Amphetamine, Cocaine |
| 64 | 2-MMC | 13.8% of mephedrone samples · lower than last week | Mephedrone, MDMA, Ketamine |
| 64 | Phenacetin | 16.7% of cocaine samples · higher than last week | Cocaine, Heroin, Ketamine |
| 57 | Levamisole | 19.9% of cocaine samples · lower than last week | Cocaine, Ketamine |
| 44 | Cocaine | 13.1% of ketamine samples · higher than last week | Ketamine, Heroin, Amphetamine |
| 42 | Amphetamine | 5.4% of MDMA samples · lower than last week | MDMA, Ketamine, Cocaine |
| 38 | 4-BEC | 19.5% of mephedrone samples · lower than last week | Mephedrone |
| 36 | 2C-B | 8.7% of MDMA samples · lower than last week | MDMA, Ketamine, Amphetamine |
| 34 | 4-MMC | 6.6% of MDMA samples · higher than last week | MDMA, Ketamine, Cocaine |
| 33 | DPIA | 7.5% of amphetamine samples | Amphetamine |
| 29 | 1-PEA | 6.4% of amphetamine samples | Amphetamine, MDMA |
| 27 | d-8-Tetrahydrocannabinol | 31% of THC samples · lower than last week | THC/cannabinoids |
| 24 | NEP | 7.2% of mephedrone samples · lower than last week | Mephedrone, MDMA, Ketamine |
Impurities Detected This Week
MDMA: 4-CMC (1), Ketamine (1), PMMA (1), Synthesis Impurity (1), Unknown (1)
Amphetamine: 1-PEA (3), Caffeine (8), DPIA (1), Unknown (1)
Cocaine: Caffeine (4), Levamisole (3), Phenacetin (1), Procaine (3), Unknown (1)
Ketamine: 2-MMC (1), 4-BEC (1), 4-MMC (1), MDMA (1), PMMA (1)
2C substances: Unknown (1)
LSD: iso-LSD (3)
THC/cannabinoids: d-8-Tetrahydrocannabinol (1)
Mephedrone: 4-BEC (2), 4-BMC (1), Ketamine (1), Procaine (1), Unknown (1)
Heroin: Caffeine (2), Paracetamol (1), Unknown (3)
Remaining detected substances: 2-Methoxyqualone (1), 2-MMC (4), 3-CMC (1), 4-CMC (8), Caffeine (1), Cmc (1), Creatine (1), Flualprazolam (1), GBL (1), GHB (1), NEP (2), PMMA (6), Unknown (2)
Data Sources
This report is based on drug-checking data published by: addiction-neuchatel.ch, ailaket.com, checkit.wien, contact-suchthilfe.ch, drogart.org, drogenarbeitz6.at, drugchecking.berlin, drugchecking.ch, druglab.fr, DrugsData, École des sciences criminelles (ESC), energycontrol.org, IRM Basel, knowyourstuff.nz, neutravel.net, nightlifevaud.ch, nuit-blanche.ch, Pharmazeutischen Kontrolllabor Bern, raveitsafe.ch, Reseachem GmbH, saferdancebasel.ch, SaferParty.ch, stoftest.org, tragwerk-luzern.ch, Trimbos, triptalks.at, Université Lausanne, wedinos.wales.
All of this data is available at your fingertips in the DrugsPRO app for Android, iOS, and the web.
Drug-checking results describe tested samples only and are not representative of the entire market.
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No test result can tell you a substance is safe. No substance is 100% safe.This article is published for harm reduction purposes. It does not encourage the use of psychoactive substances and does not replace medical advice.